ARG44858
anti-CD208 / LAMP3 antibody
anti-CD208 / LAMP3 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
Product Description | Mouse Monoclonal antibody recognizes CD208 / LAMP3 |
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Tested Reactivity | Hu |
Tested Application | IHC-P |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG2a |
Target Name | CD208 / LAMP3 |
Antigen Species | Human |
Epitope | TVSHTTGNTT QPSNQTTLPA TLSIALHKST TGQKPVQPTH APGTTAAAHN TTRTAAPAST VPGPTLAPQP SSVKTGIYQV LNGSRLCIKA EMGIQLIVQD KESVFSPRRY FNIDPNATQA SGNCGTRKSN |
Conjugation | Un-conjugated |
Alternate Names | LAMP3; Lysosomal Associated Membrane Protein 3; TSC403; DCLAMP; DC-LAMP; CD208; LAMP; DC-Lysosome-Associated Membrane Glycoprotein; Lysosome-Associated Membrane Glycoprotein 3; Lysosomal-Associated Membrane Protein 3; DC LAMP; LAMP-3; Protein TSC403; CD208 Antigen |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Protein A purification |
Buffer | PBS with 0.09% sodium azide |
Preservative | 0.09% sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9UQV4 Human Lysosome-associated membrane glycoprotein 3 |
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Gene Symbol | LAMP3 |
Gene Full Name | Lysosomal Associated Membrane Protein 3 |
Background | Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010] |
Function | Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F. [Uniprot] |
Cellular Localization | Cytoplasmic vesicle, Endosome, Lysosome, Membrane. [Uniprot] |
PTM | Disulfide bond, Glycoprotein. [Uniprot] |
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