ARG22844

anti-CD200 antibody [OX-104] (PE)

anti-CD200 antibody [OX-104] (PE) for Flow cytometry and Human

Overview

Product Description PE-conjugated Mouse Monoclonal antibody [OX-104] recognizes CD200
Mouse anti Human CD200 antibody, clone OX-104 recognizes the human CD200 cell surface antigen, also known as OX2.CD200 is expressed by a subset of B lymphocytes, some endothelial cells and by neurons. Studies have suggested that the CD200-CD200 ligand system is of importance in the control of macrophage and granulocyte activation.
Tested Reactivity Hu
Tested Application FACS
Host Mouse
Clonality Monoclonal
Clone OX-104
Isotype IgG1
Target Name CD200
Antigen Species Human
Conjugation PE
Alternate Names OX-2; OX-2 membrane glycoprotein; MOX1; MOX2; CD antigen CD200; MRC

Application Instructions

Application Suggestion
Tested Application Dilution
FACSNeat - 1:5
Application Note FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose
Preservative 0.09% Sodium azide
Stabilizer 1% BSA and 5% Sucrose
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4345 Human CD200

Swiss-port # P41217 Human OX-2 membrane glycoprotein

Gene Symbol CD200
Gene Full Name CD200 molecule
Background The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [UniProt]
Calculated MW 31 kDa