ARG23327
anti-CD1b + CD1c antibody [B-B5]
anti-CD1b + CD1c antibody [B-B5] for Flow cytometry and Human
Overview
| Product Description | Mouse Monoclonal antibody [B-B5] recognizes CD1b + CD1c |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Specificity | This antibody recognizes a 43-45 kDa protein. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | B-B5 |
| Isotype | IgG1 |
| Target Name | CD1b + CD1c |
| Antigen Species | Human |
| Immunogen | Thymus cells and Jurkat cell line |
| Conjugation | Un-conjugated |
| Alternate Names | T-cell surface glycoprotein CD1b; CD1A; R1; CD antigen CD1b; CD1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | FACS: Use 10 µl to label 10^6 cells or 100 µl of whole blood. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified |
| Buffer | PBS, 0.09% Sodium azide and 1% BSA. |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CD1B |
| Gene Full Name | CD1b molecule |
| Background | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008] |
| Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. [UniProt] |
| Calculated MW | 37 kDa |
