ARG65543
anti-CD157 / BST1 antibody [SY11B5]
anti-CD157 / BST1 antibody [SY11B5] for Flow cytometry,IHC-Frozen sections,Immunoprecipitation,Western blot and Human,Primates
Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody [SY11B5] recognizes CD157 / BST1 |
|---|---|
| Tested Reactivity | Hu, NHuPrm |
| Tested Application | FACS, IHC-Fr, IP, WB |
| Specificity | The mouse monoclonal antibody SY11B5 recognizes CD157, an approximately 45 kDa GPIanchored protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SY11B5 |
| Isotype | IgG1 |
| Target Name | CD157 / BST1 |
| Antigen Species | Human |
| Immunogen | Human CD157 |
| Conjugation | Un-conjugated |
| Alternate Names | cADPr hydrolase 2; ADP-ribosyl cyclase 2; Cyclic ADP-ribose hydrolase 2; BST-1; Bone marrow stromal antigen 1; CD157; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; CD antigen CD157; EC 3.2.2.6 |
Application Instructions
| Application Suggestion |
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| Application Note | WB: Under non-reducing condition. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from hybridoma culture supernatant by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q10588 Human ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
|---|---|
| Gene Symbol | BST1 |
| Gene Full Name | bone marrow stromal cell antigen 1 |
| Background | CD157 (cADPr hydrolase 2) is a GPI-anchored ectoenzyme possessing ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity. It uses NAD and cADP-ribose as substrates. CD157 is expressed on granulocytes, monocytes, macrophages, follicular dendritic cells, bone marrow stromal cells and human umbilical cord vein endothelial cells. In case of rheumatoid arthritis is expression is often higher and it is also differentially expressed in the myeloid leukemias. It may also have a signaling role. |
| Function | Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. [UniProt] |
| Research Area | Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 36 kDa |
Images (1) Click the Picture to Zoom In
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ARG65543 anti-CD157 / BST1 antibody [SY11B5] FACS image
Flow Cytometry: Human peripheral blood leukocytes stained with ARG65543 anti-CD157 / BST1 antibody [SY11B5], followed by incubation with APC labelled Goat anti-Mouse secondary antibody.
