ARG22180
anti-CD107a / LAMP1 antibody [H4A3] (FITC)
anti-CD107a / LAMP1 antibody [H4A3] (FITC) for Electron microscopy,Flow cytometry,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,African green monkey,Macaque,Rhesus Monkey
Cancer antibody; Cell Death antibody; Controls and Markers antibody; Developmental Biology antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody; Lysosome Marker antibody
Overview
| Product Description | FITC-conjugated Mouse Monoclonal antibody [H4A3] recognizes CD107a / LAMP1 |
|---|---|
| Tested Reactivity | Hu, AGMK, Macaq, R. Mk |
| Tested Application | EM, FACS, ICC/IF, IHC-Fr, IHC-P, WB |
| Specificity | Human/Rhesus/African Green Monkey/Pigtail Macaque/Sooty Mangabey CD107a |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | H4A3 |
| Isotype | IgG1, kappa |
| Target Name | CD107a / LAMP1 |
| Antigen Species | Human |
| Immunogen | Human adherent peripheral blood cells |
| Conjugation | FITC |
| Alternate Names | LGP120; CD107a; LAMPA; CD antigen CD107a; Lysosome-associated membrane glycoprotein 1; CD107 antigen-like family member A; LAMP-1; Lysosome-associated membrane protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS and 0.1% Sodium azide. |
| Preservative | 0.1% Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P11279 Human Lysosome-associated membrane glycoprotein 1 |
|---|---|
| Gene Symbol | LAMP1 |
| Gene Full Name | lysosomal-associated membrane protein 1 |
| Background | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008] |
| Function | Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. [UniProt] |
| Research Area | Cancer antibody; Cell Death antibody; Controls and Markers antibody; Developmental Biology antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody; Lysosome Marker antibody |
| Calculated MW | 45 kDa |
| PTM | O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans. The glycosylation of N-76 is essential for Lassa virus entry into cells. |
Images (2) Click the Picture to Zoom In
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ARG22180 anti-CD107a / LAMP1 antibody [H4A3] (FITC) ICC/IF image
Immunofluorescence: Human myeloid dendritic cells fixed with 4% paraformaldehyde for 15 min, permeabilized with PBS containing 100 µg/ml of digitonin and 1% BSA for 30 min. Cells were stained with ARG22180 anti-CD107a / LAMP1 antibody [H4A3] (FITC) at 1:50 dilution.
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ARG22180 anti-CD107a / LAMP1 antibody [H4A3] (FITC) FACS image
Flow Cytometry: Human T cell leukemia cell line Jurkat was intracellularly stained with ARG22180 anti-CD107a / LAMP1 antibody [H4A3] (FITC).
