ARG66092
anti-CCL4 / MIP1 beta antibody
anti-CCL4 / MIP1 beta antibody for ELISA,Neutralizing,Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CCL4 / MIP1 beta |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA, Neut, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CCL4 / MIP1 beta |
| Antigen Species | Mouse |
| Immunogen | E. coli derived recombinant Mouse CCL4 / MIP1 beta. (APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN) |
| Conjugation | Un-conjugated |
| Alternate Names | ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Ccl4 |
| Gene Full Name | chemokine (C-C motif) ligand 4 |
| Background | The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012] |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. [UniProt] |
| Calculated MW | 10 kDa |
Images (3) Click the Picture to Zoom In
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ARG66092 anti-CCL4 / MIP1 beta antibody WB image
Western blot: 250 - 0.24 ng of Mouse MIP-1β stained with ARG66092 anti-CCL4 / MIP1 beta antibody, under non-reducing conditions.
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ARG66092 anti-CCL4 / MIP1 beta antibody standard curve image
Sandwich ELISA: ARG66092 anti-CCL4 / MIP1 beta antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66093 anti-CCL4 / MCP1 beta antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
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ARG66092 anti-CCL4 / MIP1 beta antibody WB image
Western blot: 250 - 0.24 ng of Mouse MIP-1β stained with ARG66092 anti-CCL4 / MIP1 beta antibody, under reducing conditions.
