ARG55030
anti-CCL4 / MIP1 beta antibody
anti-CCL4 / MIP1 beta antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Immune System antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CCL4 / MIP1 beta |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CCL4 / MIP1 beta |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 22-48 of Human CCL4. |
| Conjugation | Un-conjugated |
| Alternate Names | C-C motif chemokine 4; MIP-1-beta; Act-2; Protein H400; Small-inducible cytokine A4; ACT2; MIP-1B; Macrophage inflammatory protein 1-beta; Immune activation protein 2; SIS-gamma; ACT-2; Mip1b; Scya4; AT744.1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Mouse bladder |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CCL4 |
| Gene Full Name | chemokine (C-C motif) ligand 4 |
| Background | The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012] |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. [UniProt] |
| Research Area | Immune System antibody |
| Calculated MW | 10 kDa |
Images (2) Click the Picture to Zoom In
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ARG55030 anti-CCL4 / MIP1 beta antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human prostate carcinoma stained with ARG55030 anti-CCL4 / MIP1 beta antibody.
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ARG55030 anti-CCL4 / MIP1 beta antibody WB image
Western blot: 15 µg of Mouse bladder lysate stained with ARG55030 anti-CCL4 / MIP1 beta antibody.
