ARG56757
anti-CCL22 / MDC antibody (Biotin)
anti-CCL22 / MDC antibody (Biotin) for ELISA,Western blot and Human
Overview
| Product Description | Biotin-conjugated Rabbit Polyclonal antibody recognizes CCL22 / MDC |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CCL22 / MDC |
| Antigen Species | Human |
| Immunogen | E.coli derived Recombinant Human MDC (CCL22). (GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLSQ) |
| Conjugation | Biotin |
| Alternate Names | CC chemokine STCP-1; Stimulated T-cell chemotactic protein 1; 3-69; Macrophage-derived chemokine; MDC; DC/B-CK; SCYA22; Small-inducible cytokine A22; ABCD-1; 7-69; 1-69; A-152E5.1; STCP-1; 5-69; C-C motif chemokine 22 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by affinity chromatography. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CCL22 |
| Gene Full Name | chemokine (C-C motif) ligand 22 |
| Background | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014] |
| Function | May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. [UniProt] |
| Calculated MW | 11 kDa |
| PTM | The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes. |
Images (4) Click the Picture to Zoom In
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ARG56757 anti-CCL22 / MDC antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human MDC stained with ARG56757 anti-CCL22 / MDC antibody (Biotin), under reducing conditions.
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ARG56757 anti-CCL22 / MDC antibody (Biotin) standard curve image
Direct ELISA: ARG56757 anti-CCL22 / MDC antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density.
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ARG56757 anti-CCL22 / MDC antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human MDC stained with ARG56757 anti-CCL22 / MDC antibody (Biotin), under non-reducing conditions.
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ARG56757 anti-CCL22 / MDC antibody (Biotin) standard curve image
Sandwich ELISA: ARG56757 anti-CCL22 / MDC antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56647 anti-CCL22 / MDC antibody as a capture antibody. Results of a typical standard run with optical density.
