ARG65055

anti-CCL20 / MIP3 alpha antibody

anti-CCL20 / MIP3 alpha antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Immune System antibody

Overview

Product Description Goat Polyclonal antibody recognizes CCL20 / MIP3 alpha
Tested Reactivity Hu
Predict Reactivity Cow, Pig
Tested Application IHC-P
Specificity This antibody is expected to recognize both isoforms (NP_004582.1; NP_001123518.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name CCL20 / MIP3 alpha
Antigen Species Human
Immunogen CLGYTDRILHPK
Conjugation Un-conjugated
Alternate Names ST38; CC chemokine LARC; Exodus; Macrophage inflammatory protein 3 alpha; 2-70; MIP-3a; Beta-chemokine exodus-1; SCYA20; MIP-3-alpha; LARC; MIP3A; 1-64; Small-inducible cytokine A20; 1-67; CKb4; C-C motif chemokine 20; Liver and activation-regulated chemokine

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P6 - 8 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6364 Human CCL20

Swiss-port # P78556 Human C-C motif chemokine 20

Background This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Research Area Immune System antibody
Calculated MW 11 kDa
PTM C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.

Images (1) Click the Picture to Zoom In

  • ARG65055 anti-CCL20 / MIP3 alpha antibody IHC-P image

    Immunohistochemistry: Paraffin embedded Human Liver. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG65055 anti-CCL20 / MIP3 alpha antibody at 6 µg/ml dilution followed by AP-staining.