ARG65986
anti-CCL16 / LEC antibody [1.2_5G3-1D7]
anti-CCL16 / LEC antibody [1.2_5G3-1D7] for ELISA,Neutralizing,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1.2_5G3-1D7] recognizes CCL16 / LEC |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, Neut, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1.2_5G3-1D7 |
| Isotype | IgG1, kappa |
| Target Name | CCL16 / LEC |
| Antigen Species | Human |
| Immunogen | E. coli derived recombinant Human CCL16 / LEC. (QPKVPEWVNT PSTCCLKYYE KVLPRRLVVG YRKALNCHLP AIIFVTKRNR EVCTNPNDDW VQEYIKDPNL PLLPTRNLST VKIITAKNGQ PQLLNSQ) |
| Conjugation | Un-conjugated |
| Alternate Names | CKb12; HCC-4; LEC; Monotactin-1; SCYA16; Chemokine LEC; MTN-1; SCYL4; Mtn-1; Lymphocyte and monocyte chemoattractant; Small-inducible cytokine A16; Liver-expressed chemokine; IL-10-inducible chemokine; C-C motif chemokine 16; NCC4; LCC-1; ILINCK; LMC; Chemokine CC-4; NCC-4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Gene Symbol | CCL16 |
| Gene Full Name | chemokine (C-C motif) ligand 16 |
| Background | This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008] |
| Function | Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES. [UniProt] |
| Calculated MW | 14 kDa |
Images (2) Click the Picture to Zoom In
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ARG65986 anti-CCL16 / LEC antibody [1.2_5G3-1D7] WB image
Western blot: 250 - 0.24 ng (left to right) of Human LEC stained with ARG65986 anti-CCL16 / LEC antibody [1.2_5G3-1D7], under non-reducing conditions.
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ARG65986 anti-CCL16 / LEC antibody [1.2_5G3-1D7] standard curve image
Sandwich ELISA: ARG65986 anti-CCL16 / LEC antibody [1.2_5G3-1D7] as a capture antibody at 2.0 - 4.0 µg/ml combined with anti-CCL16 / LEC antibody (Biotin) as a detection antibody at ~ 0.5 - 1.0 µg/ml. Results of a typical standard run with optical density reading at 405 - 650 nm.
