ARG57346

anti-CCBL1 antibody

anti-CCBL1 antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes CCBL1
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CCBL1
Antigen Species Human
Immunogen Recombinant Protein of Human CCBL1.
Conjugation Un-conjugated
Alternate Names Kynurenine--oxoglutarate transaminase 1; KAT1; GTK; EC 2.6.1.64; Kynurenine aminotransferase I; EC 4.4.1.13; KATI; Glutamine--phenylpyruvate transaminase; Kynurenine--oxoglutarate transaminase I; EC 2.6.1.7; Glutamine transaminase K; Cysteine-S-conjugate beta-lyase

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control SW620

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 311844 Rat CCBL1

GeneID: 70266 Mouse CCBL1

GeneID: 883 Human CCBL1

Gene Symbol CCBL1
Gene Full Name cysteine conjugate-beta lyase, cytoplasmic
Background This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Function Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. [UniProt]
Calculated MW 48 kDa

Images (2) Click the Picture to Zoom In

  • ARG57346 anti-CCBL1 antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG57346 anti-CCBL1 antibody.

  • ARG57346 anti-CCBL1 antibody WB image

    Western blot: SW620 cell lysate stained with ARG57346 anti-CCBL1 antibody.