ARG67209
anti-CCBE1 antibody
anti-CCBE1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CCBE1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | CCBE1 |
| Antigen Species | Human |
| Immunogen | Recombinant fragment corresponding to aa. C159-L251 of human CCBE1. |
| Conjugation | Un-conjugated |
| Alternate Names | CCBE1; Collagen And Calcium Binding EGF Domains 1; KIAA1983; Collagen And Calcium-Binding EGF Domain-Containing Protein 1; Full Of Fluid Protein Homolog; FLJ30681; HKLLS1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Powder |
|---|---|
| Purification | Protein A purified |
| Buffer | PBS |
| Reconstitution | Water |
| Concentration | 0.1 - 1.0 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6UXH8 Human Collagen and calcium-binding EGF domain-containing protein 1 |
|---|---|
| Gene Symbol | CCBE1 |
| Gene Full Name | Collagen And Calcium Binding EGF Domains 1 |
| Background | This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans. [provided by RefSeq, Mar 2010] |
| Function | Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 44 kDa |
| PTM | Disulfide bond; Glycoprotein; Proteoglycan. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG67209 anti-CCBE1 antibody IHC-P image
Immunohistochemistry: Human skin stained with ARG67209 anti-CCBE1 antibody at 1:100 dilution.
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ARG67209 anti-CCBE1 antibody WB image
Western blot: CCBE1 recombinant protein stained with ARG67209 anti-CCBE1 antibody.
