ARG63873
anti-CB1 Receptor antibody
anti-CB1 Receptor antibody for Western blot and Rat
Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes CB1 Receptor |
|---|---|
| Tested Reactivity | Rat |
| Predict Reactivity | Hu, Ms, Dog |
| Tested Application | WB |
| Specificity | This antibody is expected to recognise both reported isoforms. Isoform a (NP_057167.2; NP_001153732.1; NP_001153731.1; NP_001153730.1; NP_001153698.1) and isoform b (NP_149421.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CB1 Receptor |
| Antigen Species | Human |
| Immunogen | C-HTSEDGKVQVTRPDQ |
| Conjugation | Un-conjugated |
| Alternate Names | CB1K5; CNR; CB1R; Cannabinoid receptor 1; CB-R; CB1; CB1A; CANN6 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009] |
| Research Area | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody |
| Calculated MW | 53 kDa |
| PTM | Palmitoylation at Cys-415 is important for recruitment at both plasma membrane and lipid rafts. |
Images (1) Click the Picture to Zoom In
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ARG63873 anti-CB1 Receptor antibody WB image
Western blot: Rat Brain lysate (35 µg protein in RIPA buffer) stained with ARG63873 anti-CB1 Receptor antibody at 0.1 µg/ml dilution.
