ARG63249
anti-CAPON / NOS1AP antibody
anti-CAPON / NOS1AP antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes CAPON / NOS1AP |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow |
| Tested Application | IHC-P |
| Specificity | This antibody is expected to recognise both reported isoforms. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CAPON / NOS1AP |
| Antigen Species | Human |
| Immunogen | PSKTKYNLVDDGH-C |
| Conjugation | Un-conjugated |
| Alternate Names | Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; Nitric oxide synthase 1 adaptor protein; 6330408P19Rik; CAPON; C-terminal PDZ ligand of neuronal nitric oxide synthase protein |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Tris/EDTA buffer (pH 9.5). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O75052 Human Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein |
|---|---|
| Background | This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009] |
| Research Area | Neuroscience antibody |
| Calculated MW | 56 kDa |
Images (1) Click the Picture to Zoom In
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ARG63249 anti-CAPON / NOS1AP antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Brain. (Steamed antigen retrieval with Tris/EDTA buffer pH 9.5) stained with ARG63249 anti-CAPON / NOS1AP antibody at 4 µg/ml dilution followed by HRP-staining.
