ARG57165
anti-CAPG antibody [1D10]
anti-CAPG antibody [1D10] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1D10] recognizes CAPG |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1D10 |
| Isotype | IgG2b, kappa |
| Target Name | CAPG |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-348 of Human CAPG |
| Conjugation | Un-conjugated |
| Alternate Names | AFCP; Macrophage-capping protein; HEL-S-66; Actin regulatory protein CAP-G; MCP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CAPG |
| Gene Full Name | capping protein (actin filament), gelsolin-like |
| Background | This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012] |
| Function | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. [UniProt] |
| Calculated MW | 38 kDa |
| PTM | The N-terminus is blocked. |
Images (1) Click the Picture to Zoom In
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ARG57165 anti-CAPG antibody [1D10] WB image
Western blot: 40 µg of 1) HeLa, 2) NIH3T3, 3) Mouse spleen tissue lysate, 4) THP-1, and 5) Raw 264.7 cell lysates stained with ARG57165 anti-CAPG antibody [1D10] at 1:1000.
