ARG57300
anti-CA3 / Carbonic Anhydrase 3 antibody
anti-CA3 / Carbonic Anhydrase 3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CA3 / Carbonic Anhydrase 3 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CA3 / Carbonic Anhydrase 3 |
| Antigen Species | Human |
| Immunogen | Recombinant Protein of Human CA3 / Carbonic Anhydrase 3. |
| Conjugation | Un-conjugated |
| Alternate Names | CAIII; EC 4.2.1.1; Car3; CA-III; Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Mouse skeletal muscle |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CA3 |
|---|---|
| Gene Full Name | carbonic anhydrase III |
| Background | Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008] |
| Function | Reversible hydration of carbon dioxide. [UniProt] |
| Calculated MW | 30 kDa |
| PTM | S-glutathionylated in hepatocytes under oxidative stress. |
Images (2) Click the Picture to Zoom In
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ARG57300 anti-CA3 / Carbonic Anhydrase 3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat heart stained with ARG57300 anti-CA3 / Carbonic Anhydrase 3 antibody at 1:100 dilution.
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ARG57300 anti-CA3 / Carbonic Anhydrase 3 antibody WB image
Western blot: Mouse skeletal muscle lysate stained with ARG57300 anti-CA3 / Carbonic Anhydrase 3 antibody.
