ARG42755
anti-Biglycan antibody
anti-Biglycan antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Biglycan |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Biglycan |
| Antigen Species | Human |
| Immunogen | Fusion protein of Human Biglycan. |
| Conjugation | Un-conjugated |
| Alternate Names | Biglycan; Bone/cartilage proteoglycan I; SLRR1A; PGI; DSPG1; PG-S1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | WB: HeLa IHC-P: Human gastric cancer and human thyroid cancer |
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| Observed Size | ~ 45 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Concentration | 0.6 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BGN |
| Gene Full Name | biglycan |
| Background | This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015] |
| Function | May be involved in collagen fiber assembly. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. [UniProt] |
| Calculated MW | 42 kDa |
| PTM | The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG42755 anti-Biglycan antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human gasrtic cancer tissue stained with ARG42755 anti-Biglycan antibody (left) at 1:50 dilution, or the same antibody pre-incubated with fusion protein (right). (Original magnification: X200).
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ARG42755 anti-Biglycan antibody WB image
Western blot: 40 µg of HeLa cell lysate stained with ARG42755 anti-Biglycan antibody at 1:550 dilution.
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ARG42755 anti-Biglycan antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human thyroid cancer tissue stained with ARG42755 anti-Biglycan antibody (left) at 1:50 dilution, or the same antibody pre-incubated with fusion protein (right). (Original magnification: X200).
