ARG40199
anti-BOB1 antibody
anti-BOB1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes BOB1 |
---|---|
Tested Reactivity | Rat |
Predict Reactivity | Ms, Hm |
Tested Application | IHC-P |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | BOB1 |
Antigen Species | Mouse |
Immunogen | Synthetic peptide corresponding to aa. 238-256 of Mouse BOB1. (EEEESNTYELNHTLSVEGF) |
Conjugation | Un-conjugated |
Alternate Names | POU domain class 2-associating factor 1; OCA-B; BOB-1; OCAB; OBF-1; OBF1; OCT-binding factor 1; B-cell-specific coactivator OBF-1; BOB1 |
Application Instructions
Application Suggestion |
|
||||
---|---|---|---|---|---|
Application Note | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
---|---|
Purification | Affinity purification with immunogen. |
Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
Stabilizer | 5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Symbol | POU2AF1 |
---|---|
Gene Full Name | POU class 2 associating factor 1 |
Function | Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. [UniProt] |
Cellular Localization | Nucleus. [UniProt] |
Calculated MW | 27 kDa |
PTM | Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. [UniProt] |
Images (1) Click the Picture to Zoom In