Overview

Product Description	Rabbit Polyclonal antibody recognizes BMP7
Tested Reactivity	Hu, Ms, Rat
Tested Application	IP, WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	BMP7
Antigen Species	Human
Immunogen	Synthetic peptide derived from Human BMP7.
Conjugation	Un-conjugated
Alternate Names	BMP-7; OP-1; Osteogenic protein 1; Eptotermin alfa; Bone morphogenetic protein 7

Application Instructions

Application Suggestion	Tested Application Dilution IP 1:50 WB 1:500 - 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form	Liquid
Purification	Affinity purified.
Buffer	PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 12162 Mouse BMP7 GeneID: 655 Human BMP7 Swiss-port # P18075 Human Bone morphogenetic protein 7 Swiss-port # P23359 Mouse Bone morphogenetic protein 7
Gene Symbol	BMP7
Gene Full Name	bone morphogenetic protein 7
Background	The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]
Function	Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. [UniProt]
Cellular Localization	Secreted. [UniProt]
Calculated MW	49 kDa
PTM	Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms. [UniProt]

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