ARG55788

anti-BLVRB antibody

anti-BLVRB antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes BLVRB
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name BLVRB
Antigen Species Human
Immunogen Recombinant protein of Human BLVRB (NP_000704.1)
Conjugation Un-conjugated
Alternate Names FLR; BVRB; SDR43U1; HEL-S-10; Flavin reductase (NADPH); FR; EC 1.5.1.30; Biliverdin reductase B; BVR-B; EC 1.3.1.24; Biliverdin-IX beta-reductase; Green heme-binding protein; GHBP; NADPH-dependent diaphorase; NADPH-flavin reductase; FLR

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control MCF7
Observed Size ~ 22 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 233016 Mouse BLVRB

GeneID: 645 Human BLVRB

Swiss-port # P30043 Human Flavin reductase (NADPH)

Swiss-port # Q923D2 Mouse Flavin reductase (NADPH)

Gene Symbol BLVRB
Gene Full Name biliverdin reductase B
Background The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009]
Function Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin. [UniProt]
Calculated MW 22 kDa

Images (2) Click the Picture to Zoom In

  • ARG55788 anti-BLVRB antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver cancer tissue stained with ARG55788 anti-BLVRB antibody at 1:100 dilution.

  • ARG55788 anti-BLVRB antibody WB image

    Western blot: MCF7 cell lysate stained with ARG55788 anti-BLVRB antibody.