ARG45240
anti-BI 1 antibody
anti-BI 1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Polyclonal antibody recognizes BI 1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BI 1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to N-terminal region of human BI 1. |
| Conjugation | Un-conjugated |
| Alternate Names | TMBIM6; Transmembrane BAX Inhibitor Motif Containing 6 ; Testis-enhanced gene transcript protein; Bax inhibitor 1; Transmembrane BAX inhibitor motif-containing protein 6; TEGT; BI-1; BAXI1; TMBIM6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 35 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TMBIM6 |
| Gene Full Name | Transmembrane BAX Inhibitor Motif Containing 6 |
| Background | BI-1 (Bax inhibitor-1), also designated TEGT for testis enhanced gene transcript, was identified as an additional inhibitor of apoptosis. BI-1 interacts with Bcl-2 and Bcl-xL, but not with Bax or Bak, to inhibit Bax induced apoptosis. |
| Function | Suppressor of apoptosis . [UniProt] |
| Cellular Localization | Endoplasmic reticulum ; Membrane. [UniProt] |
| Calculated MW | 27 kDa |
| PTM | Isopeptide bond ; Ubl conjugation. [UniProt] |
Images (3) Click the Picture to Zoom In
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ARG45240 anti-BI 1 antibody IHC-P image
Immunohistochemistry: Human endometrial adenocarcinoma stained with ARG45240 anti-BI 1 antibody at 2 μg/ml dilution.
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ARG45240 anti-BI 1 antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45240 anti-BI 1 antibody at 5 ug/ml dilution.
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ARG45240 anti-BI 1 antibody WB image
Western blot: RT4 and CACO-2 stained with ARG45240 anti-BI 1 antibody at 0.5 μg/ml dilution.
