ARG63315
anti-BCAR3 antibody
anti-BCAR3 antibody for Western blot and Mouse
Controls and Markers antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes BCAR3 |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Hu, Cow, Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BCAR3 |
| Antigen Species | Human |
| Immunogen | C-RKLEPPPVKQAEL |
| Conjugation | Un-conjugated |
| Alternate Names | SH2 domain-containing protein 3B; Novel SH2-containing protein 2; Breast cancer anti-estrogen resistance protein 3; SH2D3B; NSP2 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9QZK2 Mouse Breast cancer anti-estrogen resistance protein 3 |
|---|---|
| Background | Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
| Research Area | Controls and Markers antibody |
| Calculated MW | 93 kDa |
Images (1) Click the Picture to Zoom In
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ARG63315 anti-BCAR3 antibody WB image
Western Blot: Mouse Kidney epithelial cells lysate (15µg protein in RIPA buffer) stained with ARG63315 anti-BCAR3 antibody at 0.5 µg/ml dilution.
