ARG45226
anti-BBS9 antibody
anti-BBS9 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Monkey
Overview
| Product Description | Rabbit Polyclonal antibody recognizes BBS9 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Mk |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BBS9 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human BBS9. |
| Conjugation | Un-conjugated |
| Alternate Names | BBS9; Bardet-Biedl Syndrome 9; PTHB1; B1; Parathyroid Hormone-Responsive B1 Gene Protein; Bardet-Biedl Syndrome 9 Protein; Protein PTHB1; Parathyroid Hormone Responsive B1 Gene; PTH-Responsive Osteosarcoma B1 Protein; C18; D1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 99 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | BBS9 |
| Gene Full Name | Bardet-Biedl Syndrome 9 |
| Background | This gene is downregulated by parathyroid hormone in osteoblastic cells, and therefore is thought to be involved in parathyroid hormone action in bones. The exact function of this gene has not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2017] |
| Function | The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization. [UniProt] |
| Cellular Localization | Cell membrane; Cell projection; Cilium; Cytoplasm; Cytoskeleton. [UniProt] |
| Calculated MW | 99 kDa |
Images (6) Click the Picture to Zoom In
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ARG45226 anti-BBS9 antibody IHC-P image
Immunohistochemistry: Human rectal cancer stained with ARG45226 anti-BBS9 antibody at 2 μg/ml dilution.
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ARG45226 anti-BBS9 antibody WB image
Western blot: SiHa and Hela stained with ARG45226 anti-BBS9 antibody at 0.5 μg/ml dilution.
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ARG45226 anti-BBS9 antibody FACS image
Flow Cytometry: RT4 stained with ARG45226 anti-BBS9 antibody at 1 µg/10^6 cells dilution.
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ARG45226 anti-BBS9 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45226 anti-BBS9 antibody at 2 μg/ml dilution.
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ARG45226 anti-BBS9 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45226 anti-BBS9 antibody at 2 μg/ml dilution.
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ARG45226 anti-BBS9 antibody WB image
Western blot: Cos-7 stained with ARG45226 anti-BBS9 antibody at 0.5 μg/ml dilution.
