ARG57172
anti-BAG2 antibody [29E9]
anti-BAG2 antibody [29E9] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [29E9] recognizes BAG2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 29E9 |
| Isotype | IgG2a, kappa |
| Target Name | BAG2 |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-211 of Human BAG2 |
| Conjugation | Un-conjugated |
| Alternate Names | BAG family molecular chaperone regulator 2; dJ417I1.2; Bcl-2-associated athanogene 2; BAG-2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95816 Human BAG family molecular chaperone regulator 2 |
|---|---|
| Gene Symbol | BAG2 |
| Gene Full Name | BCL2-associated athanogene 2 |
| Background | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008] |
| Function | Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. [UniProt] |
| Calculated MW | 24 kDa |
Images (1) Click the Picture to Zoom In
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ARG57172 anti-BAG2 antibody [29E9] WB image
Western blot: 40 µg of 1) Jurkat, 2) A549, 3) K562, 4) HepG2, and 5) HeLa cell lysates stained with ARG57172 anti-BAG2 antibody [29E9] at 1:1000.
