ARG63163

anti-B56 beta isoform antibody

anti-B56 beta isoform antibody for Western blot and Human

Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes B56 beta isoform
Tested Reactivity Hu
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name B56 beta isoform
Antigen Species Human
Immunogen C-QRLTPQVAASGGQS
Conjugation Un-conjugated
Alternate Names PP2A B subunit isoform PR61-beta; PP2A B subunit isoform B56-beta; PR61B; B56B; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; PP2A B subunit isoform R5-beta; PP2A B subunit isoform B'-beta

Application Instructions

Application Suggestion
Tested Application Dilution
WB2 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5526 Human PPP2R5B

Swiss-port # Q15173 Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta iso

Background The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. [provided by RefSeq, Jul 2008]
Research Area Neuroscience antibody; Signaling Transduction antibody
Calculated MW 57 kDa
PTM Ubiquitinated by E3 CUL3-KLHL15 complex; this modification leads to proteasomal degradation.

Images (1) Click the Picture to Zoom In

  • ARG63163 anti-B56 beta isoform antibody WB image

    Western Blot: Human Cerebellum lysate (35 µg protein in RIPA buffer) stained with ARG63163 anti-B56 beta isoform antibody at 2 µg/ml dilution.