ARG59291
anti-Arginase 1 antibody
anti-Arginase 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Arginase 1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Arginase 1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human Arginase 1. |
| Conjugation | Un-conjugated |
| Alternate Names | EC 3.5.3.1; Type I arginase; Arginase-1; Liver-type arginase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 37 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ARG1 |
| Gene Full Name | arginase 1 |
| Background | Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
| Cellular Localization | Cytoplasm. Cytoplasmic granule. Note=Localized in azurophil granules of neutrophils (PubMed:15546957). [UniProt] |
| Calculated MW | 35 kDa |
Images (2) Click the Picture to Zoom In
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ARG59291 anti-Arginase 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver stained with ARG59291 anti-Arginase 1 antibody.
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ARG59291 anti-Arginase 1 antibody WB image
Western blot: Human fetal liver and Human fetal lung lysates stained with ARG59291 anti-Arginase 1 antibody.
