ARG43958
anti-Apolipoprotein E antibody
anti-Apolipoprotein E antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Apolipoprotein E |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Apolipoprotein E |
| Antigen Species | Human |
| Immunogen | Human Apolipoprotein E recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Apolipoprotein E |
| Alternate Names | APOE; Apolipoprotein E; AD2; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); Apolipoprotein E3; LDLCQ5; APO-E; ApoE4; Apo-E; LPG |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | APOE |
| Gene Full Name | Apolipoprotein E |
| Background | The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
| Function | APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. |
| Cellular Localization | Chylomicron, Endosome, Extracellular matrix, HDL, Secreted, VLDL |
| Calculated MW | 36 kDa |
| PTM | Glycation, Glycoprotein, Oxidation, Phosphoprotein |
Images (3) Click the Picture to Zoom In
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ARG43958 anti-Apolipoprotein E antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43958 anti-Apolipoprotein E antibody at 5 μg/ml dilution.
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ARG43958 anti-Apolipoprotein E antibody WB image
Western blot: Caco-2 stained with ARG43958 anti-Apolipoprotein E antibody at 0.5 μg/mL dilution.
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ARG43958 anti-Apolipoprotein E antibody FACS image
Flow Cytometry: Coca-2 cells stained with ARG43958 anti-Apolipoprotein E antibody (blue) at 1 μg/1x10^6 cells dilution.
