ARG67065

anti-ApoJ / Clusterin antibody [SQab30335]

anti-ApoJ / Clusterin antibody [SQab30335] for IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Recombinant Rabbit Monoclonal antibody [SQab30335] recognizes ApoJ / Clusterin
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab30335
Isotype IgG
Target Name ApoJ / Clusterin
Antigen Species Human
Immunogen Recombinant protein fragment of ApoJ / Clusterin
Conjugation Un-conjugated
Protein Full Name ApoJ / Clusterin
Alternate Names Clusterin; Apolipoprotein J; SGP-2; SP-40; APOJ; ApoJbeta; CLU2; CLU1; NA1/NA2; TRPM2; CLI; SGP2; Apo-J; TRPM-2; ApoJalpha; Aging-associated gene 4 protein; APO-J; Complement cytolysis inhibitor a chain; Ku70-binding protein 1; Complement cytolysis inhibitor b chain; Testosterone-repressed prostate message 2; Complement-associated protein SP-40;40; KUB1; AAG4; Complement cytolysis inhibitor

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100-1:200
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05% BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1191 Human CLU

Swiss-port # P10909 Human Clusterin

Gene Symbol CLU
Gene Full Name clusterin
Background The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]
Function Intracellular forms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins.[UniProt]
Cellular Localization Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Membrane, Microsome, Mitochondrion, Nucleus, Secreted . [UniProt]
Calculated MW 52 kDa
PTM Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation. [Uniprot]

Images (1) Click the Picture to Zoom In

  • ARG67065 anti-ApoJ / Clusterin antibody [SQab30335] IHC-P image

    Immunohistochemistry: Human ALCL stained with ARG67065 anti-ApoJ / Clusterin antibody [SQab30335] at 1:100 dilution.