ARG54646
anti-ATP11B antibody
anti-ATP11B antibody for ELISA,ICC/IF,Western blot and Human,Mouse
Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ATP11B |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ELISA, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ATP11B |
| Antigen Species | Human |
| Immunogen | Synthetic peptide (19 aa) within aa. 290-340 of Human ATP11B protein. |
| Conjugation | Un-conjugated |
| Alternate Names | ATPIF; Probable phospholipid-transporting ATPase IF; ATPase IR; ATPase class VI type 11B; ATPIR; EC 3.6.3.1; P4-ATPase flippase complex alpha subunit ATP11B |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | K562 Cell Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Immunogen affinity purified |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9Y2G3 Human Probable phospholipid-transporting ATPase IF |
|---|---|
| Gene Symbol | ATP11B |
| Gene Full Name | ATPase, class VI, type 11B |
| Background | ATP11B Antibody: ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions. |
| Research Area | Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 134 kDa |
Images (3) Click the Picture to Zoom In
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ARG54646 anti-ATP11B antibody ICC/IF image
Immunocytochemistry: ATP11B in K562 cells stained with ARG54646 anti-ATP11B antibody at 10 μg/ml.
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ARG54646 anti-ATP11B antibody ICC/IF image
Immunofluorescence: ATP11B in K562 cells stained with ARG54646 anti-ATP11B antibody at 20 μg/ml.
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ARG54646 anti-ATP11B antibody WB image
Western blot: 1) K562 cell tissue lysate without blocking peptide 2) K562 cell tissue lysate with blocking peptide stained with ARG54646 anti-ATP11B antibody.
Lysates/proteins at 15 µg per lane.
