ARG44481

anti-ASUN / INTS13 antibody

anti-ASUN / INTS13 antibody for ICC/IF,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes ASUN / INTS13
Tested Reactivity Hu
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ASUN / INTS13
Antigen Species Human
Immunogen Human ASUN / INTS13 recombinant protein
Conjugation Un-conjugated
Alternate Names INTS13; Integrator Complex Subunit 13; C12orf11; Mat89Bb; SPATA30; NET48; ASUN; Asunder, Spermatogenesis Regulator Homolog (Drosphila); Cell Cycle Regulator Mat89Bb Homolog; Spermatogenesis Associated 30; Sarcoma Antigen NY-SAR-95; Protein Asunder Homolog; Germ Cell Tumor 1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF5 µg/ml
WB0.25-0.5 µg/ml
Application Note The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
Preservative 0.05% Sodium azide
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

Bioinformation

Database Links

GeneID: 55726 Human ASUN

Swiss-port # Q9NVM9 Human Protein asunder homolog

Gene Symbol INTS13
Gene Full Name Integrator Complex Subunit 13
Background Involved in regulation of mitotic cell cycle. Acts upstream of or within centrosome localization; mitotic spindle organization; and protein localization to nuclear envelope. Located in cytoplasm and nuclear body.
Function Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Cellular Localization Cytoplasm, Nucleus
Calculated MW 80 kDa
PTM Isopeptide bond, Phosphoprotein, Ubl conjugation

Images (2) Click the Picture to Zoom In

  • ARG44481 anti-ASUN / INTS13 antibody ICC/IF image

    Immunofluorescence: U2OS stained with ARG44481 anti-ASUN / INTS13 antibody at 5 μg/mL dilution.

  • ARG44481 anti-ASUN / INTS13 antibody WB image

    Western blot: HeLa, PC-3, A549 and A562 stained with ARG44481 anti-ASUN / INTS13 antibody at 0.5 μg/mL dilution.