ARG64462
anti-ASRGL1 / ALP antibody
anti-ASRGL1 / ALP antibody for Western blot and Human
Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes ASRGL1 / ALP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Specificity | Both reported variants represent identical protein (NP_001077395.1 and NP_079356.3). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ASRGL1 / ALP |
| Antigen Species | Human |
| Immunogen | EKHEKGAQKTDCQ |
| Conjugation | Un-conjugated |
| Alternate Names | ALP1; CRASH; Beta-aspartyl-peptidase; Isoaspartyl peptidase/L-asparaginase; Asparaginase-like protein 1; EC 3.4.19.5; EC 3.5.1.1; Isoaspartyl dipeptidase; L-asparagine amidohydrolase; ALP |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q7L266 Human Isoaspartyl peptidase/L-asparaginase |
|---|---|
| Gene Symbol | ASRGL1 |
| Gene Full Name | asparaginase like 1 |
| Function | Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. [UniProt] |
| Research Area | Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 32 kDa |
| PTM | Cleaved into an alpha and beta chain by autocatalysis; this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity. |
Images (1) Click the Picture to Zoom In
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ARG64462 anti-ASRGL1 / ALP antibody WB image
Western Blot: Human Tonsil lysate (35 µg protein in RIPA buffer) stained with ARG64462 anti-ASRGL1 / ALP antibody at 0.5 µg/ml dilution.
