ARG43894
anti-APLP1 antibody
anti-APLP1 antibody for ELISA,Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes APLP1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | APLP1 |
| Antigen Species | Human |
| Immunogen | Human APLP1 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Amyloid beta precursor like protein 1 |
| Alternate Names | APLP1; Amyloid Beta Precursor Like Protein 1; APLP; Amyloid Beta (A4) Precursor-Like Protein 1; Amyloid-Like Protein 1; Amyloid Precursor-Like Protein 1; APLP-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | APLP1 |
| Gene Full Name | Amyloid Beta Precursor Like Protein 1 |
| Background | This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Function | Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. |
| Cellular Localization | Cell membrane, Cytoplasm, Membrane |
| Calculated MW | 72 kDa |
| PTM | Disulfide bond, Glycoprotein |
Images (4) Click the Picture to Zoom In
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ARG43894 anti-APLP1 antibody WB image
Western blot: SH-SY5Y and U-87MG stained withARG43894 anti-APLP1 antibody at 0.5 μg/mL dilution.
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ARG43894 anti-APLP1 antibody FACS image
Flow Cytometry: SiHa cells stained withARG43894 anti-APLP1 antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43894 anti-APLP1 antibody WB image
Western blot: Mousebrain stained withARG43894 anti-APLP1 antibody at 0.5 μg/mL dilution.
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ARG43894 anti-APLP1 antibody WB image
Western blot: Rat brain and Rat liver stained withARG43894 anti-APLP1 antibody at 0.5 μg/mL dilution.
