ARG62361
anti-APC11 antibody
anti-APC11 antibody for Western blot and Human,Mouse
Cell Biology and Cellular Response antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes APC11 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | APC11 |
| Antigen Species | Human |
| Immunogen | A peptide from C-terminus of the human APC11. |
| Epitope | aa 76-84 |
| Conjugation | Un-conjugated |
| Alternate Names | Hepatocellular carcinoma-associated RING finger protein; APC11; Cyclosome subunit 11; Apc11p; HSPC214; Anaphase-promoting complex subunit 11 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa, NIH-3T3 cells. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified Antibody |
| Buffer | 1X PBS and 0.1% Sodium azide |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9CPX9 Mouse Anaphase-promoting complex subunit 11 Swiss-port # Q9NYG5 Human Anaphase-promoting complex subunit 11 |
|---|---|
| Gene Symbol | ANAPC11 |
| Gene Full Name | anaphase promoting complex subunit 11 |
| Function | Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody |
| Calculated MW | 10 kDa |
| PTM | Auto-ubiquitinated. |
