ARG45334
anti-ANGPT4 antibody [2H34]
anti-ANGPT4 antibody [2H34] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Rat Monoclonal antibody recognizes ANGPT4 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | IHC-P |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 2H34 |
| Isotype | IgG2 |
| Target Name | ANGPT4 |
| Antigen Species | Mouse |
| Immunogen | Recombinant Mouse ANGPT4 . |
| Conjugation | Un-conjugated |
| Alternate Names | ANGPT4; Angiopoietin 4; Angiopoietin-4; ANG3; ANG4; Angiopoietin-3; ANG-4; ANG-3 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Powder |
|---|---|
| Purification | Protein G chromatography |
| Buffer | PBS |
| Reconstitution | PBS |
| Concentration | 0.1 - 1.0 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ANGPT4 |
| Gene Full Name | Angiopoietin 4 |
| Background | Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008] |
| Function | Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 58 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG45334 anti-ANGPT4 antibody [2H34] IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45334 anti-ANGPT4 antibody [2H34].
