ARG45148
anti-AMHR2 antibody
anti-AMHR2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AMHR2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AMHR2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to C-terminal region of human AMHR2. |
| Conjugation | Un-conjugated |
| Alternate Names | AMHR2; anti-Mullerian hormone receptor, type II; MISRII; EC 2.7.11.30; MRII; AMHR; MIS type II receptor; AMH type II receptor; Anti-Muellerian hormone type-2 receptor; MISR2; Anti-Muellerian hormone type II receptor |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 65 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | AMHR2 |
| Gene Full Name | anti-Mullerian hormone receptor, type II |
| Background | This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009] |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. [UniProt] |
| Cellular Localization | Membrane. [UniProt] |
| Calculated MW | 63 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
Images (6) Click the Picture to Zoom In
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ARG45148 anti-AMHR2 antibody IHC-P image
Immunohistochemistry: Human ovarian cancer stained with ARG45148 anti-AMHR2 antibody at 1 μg/ml dilution.
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ARG45148 anti-AMHR2 antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45148 anti-AMHR2 antibody at 5 ug/ml dilution.
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ARG45148 anti-AMHR2 antibody WB image
Western blot: 293T, MCF-7, and HL-60 stained with ARG45148 anti-AMHR2 antibody at 0.5 μg/ml dilution.
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ARG45148 anti-AMHR2 antibody FACS image
Flow Cytometry: K562 stained with ARG45148 anti-AMHR2 antibody at 1 µg/10^6 cells dilution.
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ARG45148 anti-AMHR2 antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG45148 anti-AMHR2 antibody at 1 μg/ml dilution.
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ARG45148 anti-AMHR2 antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG45148 anti-AMHR2 antibody at 1 μg/ml dilution.
