ARG63298
anti-ALMS1 antibody
anti-ALMS1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody; Immune System antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes ALMS1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog |
| Tested Application | IHC-P |
| Specificity | The C terminus of ALMS1 shares an 8 amino acid stretch with two other human proteins: hypothetical protein (XP_169104) and ERAL1 (NP_005693). However, this stretch is located internally in these two proteins and so will most likely not cross-react with this antibody. The N terminus was not chosen as the peptide is expected to cyclise during synthesis. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ALMS1 |
| Antigen Species | Human |
| Immunogen | C-RVTNQLLGRKVPWD |
| Conjugation | Un-conjugated |
| Alternate Names | Alstrom syndrome protein 1; ALSS |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Microwaved tissue section in Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a protein containing a large tandem-repeat domain. The mouse ortholog of this gene has been shown to function in ciliogenesis in inner medullary collecting duct cells. Mutations in this gene have been associated with Alstrom syndrome. Alternative splice variants have been described but their full length sequences have not been determined.[provided by RefSeq, Mar 2009] |
| Research Area | Gene Regulation antibody; Immune System antibody |
| Calculated MW | 461 kDa |
Images (1) Click the Picture to Zoom In
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ARG63298 anti-ALMS1 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Testis. (Microwaved antigen retrieval with Tris/EDTA buffer pH9) stained with ARG63298 anti-ALMS1 antibody at 2 µg/ml dilution followed by HRP-staining.
