ARG40473
anti-ALDH6A1 antibody
anti-ALDH6A1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ALDH6A1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ALDH6A1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 30-59 of Human ALDH6A1. |
| Conjugation | Un-conjugated |
| Alternate Names | MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; EC 1.2.1.18; EC 1.2.1.27; MMSADHA |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Human liver | ||||||||
| Observed Size | 57 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q02252 Human Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial Swiss-port # Q9EQ20 Mouse Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial |
|---|---|
| Gene Symbol | ALDH6A1 |
| Gene Full Name | aldehyde dehydrogenase 6 family, member A1 |
| Background | This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
| Function | Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA. [UniProt] |
| Cellular Localization | Mitochondrion. [UniProt] |
| Calculated MW | 58 kDa |
Images (3) Click the Picture to Zoom In
-
ARG40473 anti-ALDH6A1 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast carcinoma tissue stained with ARG40473 anti-ALDH6A1 antibody.
-
ARG40473 anti-ALDH6A1 antibody WB image
Western blot: 20 µg of Human liver lysate stained with ARG40473 anti-ALDH6A1 antibody at 1:1000 dilution.
-
ARG40473 anti-ALDH6A1 antibody FACS image
Flow Cytometry: ATDC5 cells stained with ARG40473 anti-ALDH6A1 antibody (bottom histogram) or without primary antibody as control (top histogram), followed by incubation with FITC labelled secondary antibody.
