ARG64575
anti-AID antibody
anti-AID antibody for Western blot and Human
Gene Regulation antibody; Immune System antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes AID |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Cow, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AID |
| Antigen Species | Human |
| Immunogen | RRKFLYQFKNVR-C |
| Conjugation | Un-conjugated |
| Alternate Names | Cytidine aminohydrolase; CDA2; HIGM2; Activation-induced cytidine deaminase; AID; EC 3.5.4.38; ARP2; Single-stranded DNA cytosine deaminase; HEL-S-284 |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9GZX7 Human Single-stranded DNA cytosine deaminase |
|---|---|
| Background | This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009] |
| Research Area | Gene Regulation antibody; Immune System antibody |
| Calculated MW | 24 kDa |
| PTM | Ser-38 is the major site whereas Thr-27 is the minor site of phosphorylation. Phosphorylation regulates its class-switch recombination activity. Probably monoubiquitinated on several residues by RNF126. |
Images (1) Click the Picture to Zoom In
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ARG64575 anti-AID antibody WB image
Western Blot: Human Tonsil lysate (35 µg protein in RIPA buffer) stained with ARG64575 anti-AID antibody at 0.1 µg/ml dilution.
