ARG57400

anti-AGTRAP antibody

anti-AGTRAP antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes AGTRAP
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name AGTRAP
Antigen Species Human
Immunogen Recombinant Protein of Human AGTRAP.
Conjugation Un-conjugated
Alternate Names ATRAP; Type-1 angiotensin II receptor-associated protein; AT1 receptor-associated protein

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control BxPC-3

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11610 Mouse AGTRAP

GeneID: 298646 Rat AGTRAP

GeneID: 57085 Human AGTRAP

Gene Symbol AGTRAP
Gene Full Name angiotensin II receptor-associated protein
Background This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Function Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. [UniProt]
Calculated MW 17 kDa

Images (1) Click the Picture to Zoom In

  • ARG57400 anti-AGTRAP antibody WB image

    Western blot: BxPC-3 cell lysate stained with ARG57400 anti-AGTRAP antibody.