ARG45546
anti-ADRM1 antibody
anti-ADRM1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ADRM1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ADRM1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human ADRM1. |
| Conjugation | Un-conjugated |
| Alternate Names | ADRM1; adhesion regulating molecule 1; 110 kDa cell membrane glycoprotein; hRpn13; ARM1; ARM-1; Proteasomal ubiquitin receptor ADRM1; Gp110; Adhesion-regulating molecule 1; GP110; Rpn13 homolog; Proteasome regulatory particle non-ATPase 13 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 42 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ADRM1 |
| Gene Full Name | adhesion regulating molecule 1 |
| Background | This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Function | Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. [UniProt] |
| Cellular Localization | Cytoplasm; Nucleus; Proteasome. [UniProt] |
| Calculated MW | 42 kDa |
| PTM | Acetylation; Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
Images (8) Click the Picture to Zoom In
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ARG45546 anti-ADRM1 antibody IHC-P image
Immunohistochemistry: Human lung cancer stained with ARG45546 anti-ADRM1 antibody at 2 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody ICC/IF image
Immunofluorescence: CACO-2 stained with ARG45546 anti-ADRM1 antibody at 5 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody WB image
Western blot: HEK293 stained with ARG45546 anti-ADRM1 antibody at 0.5 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody FACS image
Flow Cytometry: A431 stained with ARG45546 anti-ADRM1 antibody at 1 µg/10^6 cells dilution.
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ARG45546 anti-ADRM1 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45546 anti-ADRM1 antibody at 2 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody WB image
Western blot: Rat ovary stained with ARG45546 anti-ADRM1 antibody at 0.5 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45546 anti-ADRM1 antibody at 2 μg/ml dilution.
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ARG45546 anti-ADRM1 antibody WB image
Western blot: RAW264.7 stained with ARG45546 anti-ADRM1 antibody at 0.5 μg/ml dilution.
