ARG66526
anti-ADCY1 antibody
anti-ADCY1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ADCY1 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ADCY1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within aa. 200-280 of Human ADCY1. |
| Conjugation | Un-conjugated |
| Alternate Names | Adenylate cyclase type I; Ca; AC1; DFNB44; ATP pyrophosphate-lyase 1; EC 4.6.1.1; Adenylyl cyclase 1; Adenylate cyclase type 1; 2+ |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 130 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol and 0.5% BSA |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ADCY1 |
| Gene Full Name | adenylate cyclase 1 (brain) |
| Background | This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
| Function | This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity). [UniProt] |
| Cellular Localization | Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane raft. Note=Expressed in the cytoplasm of supporting cells and hair cells of the cochlea vestibule, as well as to the cochlear hair cell nuclei and stereocilia. [UniProt] |
| Calculated MW | 123 kDa |
| PTM | N-glycosylated. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG66526 anti-ADCY1 antibody WB image
Western blot: HuvEc and MCF7 cell lysates stained with ARG66526 anti-ADCY1 antibody.
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ARG66526 anti-ADCY1 antibody WB image
Western blot: COLO205 cell lysate stained with ARG66526 anti-ADCY1 antibody.
