ARG64615
anti-ABCE1/ RNAse L inhibitor antibody
anti-ABCE1/ RNAse L inhibitor antibody for Western blot and Human
Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes ABCE1/ RNAse L inhibitor |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog |
| Tested Application | WB |
| Specificity | Variants (NP_002931.2; NP_001035809.1) encode the same protein. |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ABCE1/ RNAse L inhibitor |
| Antigen Species | Human |
| Immunogen | C-KLNSIKDVEQKK |
| Conjugation | Un-conjugated |
| Alternate Names | RNS4I; ABC38; 2'-5'-oligoadenylate-binding protein; OABP; RNASEL1; Ribonuclease 4 inhibitor; RLI; ATP-binding cassette sub-family E member 1; HuHP68; RNase L inhibitor; RNASELI |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P61221 Human ATP-binding cassette sub-family E member 1 |
|---|---|
| Background | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Research Area | Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 67 kDa |
Images (1) Click the Picture to Zoom In
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ARG64615 anti-ABCE1/ RNAse L inhibitor antibody WB image
Western Blot: A431 lysate (35 µg protein in RIPA buffer) stained with ARG64615 anti-ABCE1/ RNAse L inhibitor antibody at 0.3 µg/ml dilution.
