ARG57359
anti-A RAF antibody
anti-A RAF antibody for Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes A RAF |
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Tested Reactivity | Hu |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | A RAF |
Antigen Species | Human |
Immunogen | Recombinant Protein of Human A-RAF. |
Conjugation | Un-conjugated |
Alternate Names | Proto-oncogene A-Raf; ARAF1; Proto-oncogene A-Raf-1; RAFA1; PKS2; Proto-oncogene Pks; A-RAF; EC 2.7.11.1; Serine/threonine-protein kinase A-Raf |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | MCF7 |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # P10398 Human Serine/threonine-protein kinase A-Raf |
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Gene Symbol | ARAF |
Gene Full Name | A-Raf proto-oncogene, serine/threonine kinase |
Background | This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2012] |
Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation. [UniProt] |
Calculated MW | 68 kDa |
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