ARG30069
TNF alpha ELISA Antibody Duo
Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Metabolism antibody; Signaling Transduction antibody
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG10001 | anti-TNF alpha antibody [CH8820] | Mouse mAb | Hu | ELISA, IHC-P, Neut | 100 μg |
| ARG10194 | anti-TNF alpha antibody [B1E4] (HRP) | Mouse mAb | Hu | ELISA | 100 μl |
Overview
| Product Description | Tumor Necrosis Factor-alpha (TNF-α) is a multifunctional pro-inflammatory cytokine, mainly secreted by activated macrophages. It is implicated with a variety of biological procedures including systemic inflammation, cell proliferation, apoptosis, lipid metabolism, and coagulation. The pleiotropic attribute of TNF-α regulation is associated with its ability to trigger multiple signalling pathways through its receptors, TNFR1 (p55) and TNFR2 (p75). TNF-α not only contributes to the immune response to bacterial, fungal, viral and parasitic invasions, but also functions in tissue remodeling, autoimmune-diseases and the necrosis of specific tumors. TNF-α hyper-expression in response to some bacterial components such as LPS can cause life threatening septic shock. Recombinant TNF-α, in combination with chemotherapy, has been applied for treatment of soft sarcomas, melanomas and other irresectable tumors. Anti-TNF-α therapy has been used for treatment of rheumatoid arthritis. ARG30069 TNF alpha ELISA Duos, includes a capture antibody, ARG10001 TNF alpha antibody [CH8820] and a HRP-conjugated tracer antibody, ARG10194 TNF alpha (Tracer) antibody [B1E4] (HRP), for studying Tumor Necrosis Factor-alpha (TNF-α) protein expression level by ELISA. Related news: HMGB1 in inflammation Inflammatory Cytokines |
|---|---|
| Target Name | TNF alpha |
| Alternate Names | TNF alpha ELISA antibody; TNF alpha antibody; HRP-conjugated TNF alpha antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
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| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | ELISA Antibody Duo for TNF alpha |
|---|---|
| Highlight | Related products: TNF alpha antibodies; TNF alpha ELISA Kits; TNF alpha Duos / Panels; TNF alpha recombinant proteins; |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Metabolism antibody; Signaling Transduction antibody |
