ARG83465
Rat PLXNA3 / Plexin-A3 ELISA Kit
Rat PLXNA3 / Plexin-A3 ELISA Kit for ELISA and Rat
Overview
| Product Description | ARG83465 Rat PLXNA3 / Plexin-A3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat PLXNA3 / Plexin-A3 in Serum, plasma and cell culture supernatants. |
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| Tested Reactivity | Rat |
| Tested Application | ELISA |
| Target Name | PLXNA3 / Plexin-A3 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 15 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 31.2 - 2000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| Alternate Names | PLXNA3; Plexin A3; XAP-6; Plxn3; PLXN4; SEX; 6.3; Semaphorin Receptor SEX; Plexin-A3; Plexin-4; Sex Chromosome X Transmembrane Protein Of HGF Receptor Family 3; HSSEXGENE |
Application Instructions
| Assay Time | 3.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PLXNA3 |
| Gene Full Name | Plexin A3 |
| Background | This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013] |
| Function | Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
| Cellular Localization | Cell membrane, Membrane |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein |
| Title | Download Link |
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| ARG83465 Rat PLXNA3 / Plexin-A3 ELISA Kit User manual |
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