ARG83482
Rat Antithrombin III ELISA Kit
Rat Antithrombin III ELISA Kit for ELISA and Rat
Overview
| Product Description | ARG83482 Rat Antithrombin III ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat Antithrombin III in Plasma, Serum and Urine |
|---|---|
| Tested Reactivity | Rat |
| Tested Application | ELISA |
| Target Name | Antithrombin III |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 6.25 ng/ml |
| Sample Type | Plasma, Serum and Urine |
| Standard Range | 12.5 - 400 ng/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | SERPINC1; Serpin Family C Member 1; ATIII; AT3; Serine (Or Cysteine) Proteinase Inhibitor, Clade C (Antithrombin), Member 1; Serpin Peptidase Inhibitor, Clade C (Antithrombin), Member 1; Antithrombin-III; MGC22579; Coding Sequence Signal Peptide Antithrombin Part 1; Serpin Peptidase Inhibitor Clade C Member 1; Signal Peptide Antithrombin Part 1; Antithrombin (Aa 375-432); Antithrombin III; Serpin C1; ATIII-R2; ATIII-T1; ATIII-T2; THPH7; AT3D |
Application Instructions
| Assay Time | 2 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | SERPINC1 |
|---|---|
| Gene Full Name | serpin peptidase inhibitor, clade C (antithrombin), member 1 |
| Background | The protein encoded by this gene, antithrombin III, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. Numerous mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency which constitutes a strong risk factor for thrombosis. A reduction in the serum level of this protein is associated with severe cases of Coronavirus Disease 19 (COVID-19). |
| Function | Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond, Glycoprotein, Phosphoprotein |
| Title | Download Link |
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| ARG83482 Rat Antithrombin III ELISA Kit User manual |
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