Prolactin (PRL) is primarily secreted by pituitary gland. The hormone stimulates mammary gland development during pregnancy and the lactation period after childbirth. PRL has several variations with molecular weights ranging from 22kDa to 150kDa. PRL receptors are mainly located at mammary glands, but also found in other organs and tissues. PRL can bind to cytokine-like receptors and influence haematopoiesis, angiogenesis, and immune response. Anterior pituitary tumours can cause persistent elevation of PRL with clinical signs such as abnormal lactation, infertility and lack of menstrual flow in women, and incompetence in men.

ARG30057 Prolactin ELISA Duos, includes a capture antibody, ARG10175 PRL antibody [PRL-1] and a HRP-conjugated tracer antibody, ARG10176 PRL antibody [PRL-2] (HRP), for studying the prolactin (PRL) protein expression level by ELISA.