ARG70418
Pig IGF1 recombinant protein (His-tagged, C-ter)
Pig IGF1 recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Pig IGF1 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | IGF1 |
| Species | Pig |
| A.A. Sequence | Gly49 - Ala118 |
| Expression System | E. coli |
| Protein Full Name | Insulin-like growth factor I |
| Alternate Names | IGF1; Insulin Like Growth Factor 1; IGF-I; IGFI; IGF; Insulin-Like Growth Factor 1 (Somatomedin C); Insulin-Like Growth Factor I ; Mechano Growth Factor; Somatomedin-C; IGF1A; MGF; Insulin-Like Growth Factor IB; Somatomedin C; IBP1 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | PBS (pH 8.0) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IGF1 |
|---|---|
| Gene Full Name | Insulin Like Growth Factor 1 |
| Background | The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. |
| Function | The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond |
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ARG70418 Pig IGF1 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70418 Pig IGF1 recombinant protein (His-tagged, C-ter)
