ARG70419
Pig EGF recombinant protein (His-tagged, C-ter)
Pig EGF recombinant protein (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Pig EGF recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | EGF |
| Species | Pig |
| A.A. Sequence | Asn970 - Arg1022 |
| Expression System | E. coli |
| Protein Full Name | Pro-epidermal growth factor |
| Alternate Names | EGF; Epidermal Growth Factor; Pro-Epidermal Growth Factor; Epidermal Growth Factor (Beta-Urogastrone); Beta-Urogastrone; HOMG4; URG |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >95% (by SDS-PAGE) |
| Buffer | PBS (pH 8.0) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | EGF |
|---|---|
| Gene Full Name | Epidermal Growth Factor |
| Background | This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] |
| Function | EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro |
| Cellular Localization | Membrane |
| PTM | Disulfide bond, Glycoprotein |
Images (1) Click the Picture to Zoom In
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ARG70419 Pig EGF recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70419 Pig EGF recombinant protein (His-tagged, C-ter)
