ARG70447
Pig CXCL10 / IP10 recombinant protein (Active) (His-tagged, N-ter)
Pig CXCL10 / IP10 recombinant protein (Active) (His-tagged, N-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (N-ter) Active Pig CXCL10 / IP10 recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | CXCL10 / IP10 |
| Species | Pig |
| A.A. Sequence | Pro23 - Ala104 |
| Expression System | E. coli |
| Protein Full Name | C-X-C motif chemokine 10 |
| Activity | Active |
| Activity Note | Determined by its ability to chemoattract BaF3 cells transfected with human CXCR2. The ED50 for this effect is <4 ng/mL. |
| Alternate Names | CXCL10; C-X-C Motif Chemokine Ligand 10; IP-10; GIP-10; SCYB10; IFI10 ; Crg-2; Mob-1; INP10; C7 |
Properties
| Form | Powder |
|---|---|
| Purification Note | Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | >98% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not <200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CXCL10 |
|---|---|
| Gene Full Name | C-X-C Motif Chemokine Ligand 10 |
| Background | This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. |
| Function | Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects. |
| Cellular Localization | Secreted |
| PTM | Citrullination, Disulfide bond |
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ARG70447 Pig CXCL10 / IP10 recombinant protein (Active) (His-tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70447 Pig CXCL10 / IP10 recombinant protein (Active) (His-tagged, N-ter)
